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Cha­rité - Uni­ver­si­täts­me­di­zin Ber­lin - Ber­lin Branden­burg Cen­ter for Regen­er­at­ive Ther­apies

Char­ité is one of the largest uni­versity hos­pit­als in Europe. All of our clin­ical care, research and teach­ing is delivered by phys­i­cians and research­ers of the highest inter­na­tional stand­ard. Char­ité is inter­na­tion­ally renowned for its excel­lence in teach­ing and train­ing. Char­ité – Uni­versitätsmed­izin Ber­lin rep­res­ents a single med­ical fac­ulty, which serves both Hum­boldt Uni­ver­stität zu Ber­lin and Freie Uni­versität Ber­lin.

Pos­i­tion for a highly motiv­ated ded­ic­ated post-doc­toral fel­low for a pro­ject using 2D and 3D mod­els of the brain

We are look­ing for tal­en­ted and highly motiv­ated PhDs for a pro­ject fun­ded by the Ger­man Fed­eral Min­istry of Edu­ca­tion and Research on the func­tional char­ac­ter­iz­a­tion of mito­chon­drial pro­tein com­plexes for the patho­physiology of stroke in human stem cell-derived 2D and 3D mod­els of the brain.

Work­ing field:

  • Mech­an­isms of Stroke patho­physiology and their val­id­a­tion as a thera­peutic tar­get.
  • Use of human induced pluri­po­tent stem cells (hiPSC) to gen­er­ate 2D, 3D and organoid mod­els of the brain.
  • Genetic engin­eer­ing of hiPSC with CRISPR/Cas.
  • Mul­ti­di­men­sional micro­scopy, high con­tent micro­scopy and high con­tent ana­lysis.
  • Par­ti­cip­at­ing in animal stud­ies.


  • Gradu­ate degree in Bio­logy, Bio­chem­istry, Bio­tech­no­logy, or sim­ilar.
  • PhD with excel­lent res­ults, a focus on cell bio­logy is pre­ferred.
  • Excel­lent skills in hand­ling primary cells or stem cells.
  • Expert­ise in mul­ti­di­men­sional micro­scopy and (auto­mated) data ana­lysis.
  • Track record of com­pleted pro­jects.
  • Interest in trans­la­tional research with a focus on basic bio­lo­gical mech­an­isms in the clin­ical Neur­osciences.

Per­son­al­ity, meth­od­o­lo­gical and social skills:
We are look­ing for ded­ic­ated and flex­ible per­son­al­it­ies. The ideal can­did­ates show strong motiv­a­tion and a sense of respons­ib­il­ity, joy in multi-pro­fes­sional team­work, high accur­acy and reli­ab­il­ity in their exper­i­men­tal work. Can­did­ates have strong organ­iz­a­tional and com­mu­nic­a­tion skills, and the motiv­a­tion to par­ti­cip­ate in the train­ing and super­vi­sion of new employ­ees (e.g. doc­toral stu­dents) in addi­tion to the sci­entific work.

Can­did­ates are expec­ted to show a good level of inde­pend­ence. Exact doc­u­ment­a­tion of all work, motiv­a­tion to estab­lish new tech­niques, pre­pare data ana­lyses, pro­ject reports and manuscripts inde­pend­ently, very good know­ledge of the Eng­lish lan­guage, and excel­lent com­puter skills are expec­ted.

How to ap­ply:

Please include a cover let­ter describ­ing your past research exper­i­ence and poten­tial future research interests.
Please send your applic­a­tion doc­u­ments by email in PDF format. Con­tact details are avail­able in the ori­ginal job post­ing. Please con­sult and refer to the ori­ginal job descrip­tion when apply­ing: