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Helm­holtz-Zen­trum Dres­den-Ros­sen­dorf e.V.

Through cut­ting-edge research in the fields of ENERGY, HEALTH and MAT­TER, Helm­holtz-Zen­trum Dresden-Rossen­dorf (HZDR) solves some of the press­ing soci­etal and indus­trial chal­lenges of our time. Join our 1.400 employ­ees from more than 50 nations at one of our six research sites and help us mov­ing research to the next level!

At the Insti­tute of Radio­phar­ma­ceut­ical Can­cer Research sci­ent­ists (f/m/d) from the fields of phys­ics, chem­istry, bio­logy, phar­macy, immun­o­logy, medi­cine and IT develop innov­at­ive radio­phar­ma­ceut­ic­als and novel tools for func­tional char­ac­ter­iz­a­tion, improved ima­ging and per­son­al­ized treat­ment of tumors.

As part of the Insti­tute, the Depart­ment of Radioim­mun­o­logy invites applic­a­tions as PhD Stu­dent (f/m/d) Innov­at­ive Tar­get Mod­u­lat­ors for FAPtar­get­ing Uni­CAR T ther­apy in the OncoPro­Tools pro­gram of the MSCA Doc­toral Net­work. For more inform­a­tion click here.

The pos­i­tion will be avail­able from 1 Janu­ary 2023, sub­ject to pro­ject approval. The employ­ment con­tract is lim­ited to three years.

PhD Stu­dent (f/m/d) Innov­at­ive Tar­get Mod­u­lat­ors for FAPtar­get­ing Uni­CAR T ther­apy

English

Working field:

  • Gen­er­ate and char­ac­ter­ize innov­at­ive Uni­CAR tar­get mod­ules (TMs) that allow bimodal can­cer ther­apy (CAR T cell immun­o­ther­apy and radio­ther­apy)
  • Per­form ana­lyt­ical, bio­chem­ical and bio­lo­gical invest­ig­a­tions on the Uni­CAR TMs
  • Set up advanced cel­lu­lar eval­u­ation mod­els and deliver pre­clin­ical proof (cell, in vivo) of effic­acy for newly designed Uni­CAR TMs
  • Write pro­ject reports for your local and net­work super­visors on a reg­u­lar basis
  • Suc­cess­ful can­did­ates will apply in one of two gradu­ate schools at the med­ical fac­ulty of TU Dresden (e.g. DIGGS-BB)
  • Par­ti­cip­ate act­ively to OncoPro­Tools’ train­ing, dis­sem­in­a­tion, com­mu­nic­a­tion and val­or­iz­a­tion pro­gram
  • Pre­pare a doc­toral thesis, and pub­lish sci­entific art­icles related to the research pro­ject
  • Fur­ther­more, the selec­ted can­did­ate will take part in the fol­low­ing planned second­ments:
  • Aca­demic second­ment at Uni­versity of Copen­ha­gen (6 months, Den­mark) to syn­thes­ize Uni­CAR TM1
  • Indus­trial second­ment at CROmed (5 months, Hun­gary) for the in vivo eval­u­ation of TM1

Requirements:

  • Applic­ants must hold a mas­ter’s degree or equi­val­ent in the field of Bio­logy, Bio­tech­no­logy, (Bio-) Chem­istry or equi­val­ent e.g. must have com­pleted their med­ical stud­ies
  • Mas­ter stu­dents in their final year may apply. Final selec­tion under the con­di­tion of show­ing tran­scripts of their mas­ter’s degree in July (July 15th at the latest)
  • Applic­ants must have a solid know­ledge of immun­o­logy and/or pro­tein bio­chem­istry
  • Applic­ants have obtained out­stand­ing aca­demic res­ults
  • Applic­ants must have an abil­ity to under­stand and express them­selves in both writ­ten and spoken Eng­lish to a level that is suf­fi­ciently high for them to derive the full bene­fit from the net­work train­ing
  • Applic­ants must be eli­gible to enrol on a PhD pro­gramme at the host insti­tu­tion (or at a des­ig­nated uni­versity, in case the host insti­tu­tion is a non-aca­demic organ­isa­tion)
  • Applic­ants must have the neces­sary aca­demic skills and back­ground to make the suc­cess of a doc­toral degree

What we offer:

  • A vibrant research com­munity in an open, diverse and inter­na­tional work envir­on­ment
  • Sci­entific excel­lence and extens­ive pro­fes­sional net­work­ing oppor­tun­it­ies
  • A struc­tured PhD pro­gram with a com­pre­hens­ive range of con­tinu­ing edu­ca­tion and net­work­ing oppor­tun­it­ies - more inform­a­tion about the PhD pro­gram at the HZDR can be found here
  • The employ­ment con­tract is lim­ited to three years
  • Salary and social bene­fits in accord­ance with the col­lect­ive agree­ment for the pub­lic sec­tor (TVöD-Bund) includ­ing 30 days of paid hol­i­day leave, com­pany pen­sion scheme (VBL)
  • We sup­port a good work-life bal­ance with the pos­sib­il­ity of part-time employ­ment and flex­ible work­ing hours
  • Numer­ous com­pany health man­age­ment offer­ings
  • An employer sub­sidy for the VVO job ticket

How to apply:

Kindly sub­mit your com­pleted applic­a­tion (includ­ing cover let­ter, CV, dip­lo­mas/tran­scripts, etc.) only via our Online-applic­a­tion-sys­tem. By sub­mit­ting your applic­a­tion, you are agree that all organ­isa­tions involved in the pro­ject have access to your applic­a­tion doc­u­ments. Please be sure to also place your applic­a­tion via the OncoPro­Tools portal.