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Char­ité – Uni­versitätsmed­izin Ber­lin - Depart­ment of Psy­chi­atry and Psy­cho­ther­apy

The Char­ité - Uni­versitätsmed­izin Ber­lin is a joint insti­tu­tion of the Free Uni­versity Ber­lin and the Hum­boldt Uni­versity Ber­lin. As one of Europe's largest uni­versity hos­pit­als with sig­ni­fic­ant his­tory, it plays a lead­ing role in research, teach­ing and health­care. Char­ité also emerges as a mod­ern employer with cer­ti­fic­a­tions in the med­ical, clin­ical and man­age­ment sec­tors.

Research Asso­ci­ate / Postdoc

Full-time employ­ment lim­ited to the dur­a­tion of a preg­nancy and par­ental leave replace­ment, until 31.12.2021. Sub­ject to per­sonal qual­i­fic­a­tions employ­ees are remu­ner­ated accord­ing to salary group E13 TVöD-K (VKA). City: Ber­lin, Start­ing Date: As soon as pos­sible.

Work­ing field:

Yildirim Lab has extens­ive exper­i­ence in char­ac­ter­iz­ing epi­gen­etic and tran­scrip­tional dys­reg­u­la­tion in CNS dis­eases such as Hunt­ing­ton’s Dis­ease and stroke. More inform­a­tion about our sci­entific field of work can be found on our webpage at http://ferahyildirimlab.com/.

The Postdoc pos­i­tion we offer is part of a pro­ject in which we aim to invest­ig­ate the role of epi­gen­etic mech­an­isms, espe­cially DNA methyl­a­tion, and the gene expres­sion pro­grams that are involved in alco­hol addic­tion. The pro­ject involves per­form­ing gen­ome-wide DNA methyl­a­tion assays such as reduced rep­res­ent­a­tion bisul­fite sequen­cing (RRBS) and methyl­ated DNA immun­o­precip­it­a­tion fol­lowed by sequen­cing (MeDIP-Seq). Util­iz­ing these tech­no­lo­gies, we have pre­vi­ously repor­ted large changes in DNA methyl­a­tion in mod­els of Hunt­ing­ton’s dis­ease (Ng, C.W., Yildirim F. et al., PNAS, 2013). In the cur­rent pro­ject, these tech­niques will be applied to the brain samples, which are read­ily avail­able from a rat model of alco­hol addic­tion (Hadar, R., et al., Behav Brain Res, 2017).

Require­ments:

  • Com­pleted Ph.D. degree in Neur­os­cience, Bio­logy or related field of sci­ence
  • Exper­i­ence in the field of neuro­bi­o­logy
  • Expert­ise in molecu­lar bio­logy labor­at­ory tech­niques
  • Exper­i­ence in epi­ge­n­om­ics, tran­scrip­tom­ics and/or next gen­er­a­tion sequen­cing tech­niques is desired
  • Exper­i­ence in pre­par­a­tion of manuscripts for pub­lic­a­tion is desired
  • Exper­i­ence in col­lab­or­a­tions with bioin­form­aticians for data ana­lyses is an asset
  • High motiv­a­tion, ini­ti­at­ive and abil­ity to work inde­pend­ently as well as in a team, flex­ib­il­ity, reli­ab­il­ity and good organ­iz­a­tional skills, abil­ity to work in an inter­na­tional team, flu­ency in Eng­lish – writ­ten and oral.

How to ap­ply:

Your applic­a­tion as one single pdf doc­u­ment should include:

  • Cover let­ter, describ­ing your research exper­i­ence and accom­plish­ments, includ­ing sum­mary of pre­vi­ous research done dur­ing your PhD thesis, and your research interests and career goals (max. 2 pages)
  • CV, includ­ing list of pub­lic­a­tions, cop­ies of degree cer­ti­fic­ates and tran­scripts
  • Con­tact inform­a­tion for two ref­er­ences, includ­ing cur­rent super­visor.

Please send your applic­a­tion via email to ferah.yildirim@charite.de. Please sub­mit cop­ies only, as
your applic­a­tion will not be returned to you.

DIE CHAR­ITÉ - UNI­VERSITÄTSMED­IZIN BER­LIN makes its per­son­nel decisions on the basis of suit­ab­il­ity, qual­i­fic­a­tion and pro­fes­sional per­form­ance. At the same time, an increase in the pro­por­tion of women in man­age­ment pos­i­tions and, in the case of equi­val­ent qual­i­fic­a­tions, this is taken into within the frame­work of the legal pos­sib­il­it­ies. We also expressly wel­come applic­a­tions from people with an immig­rant back­ground. Severely dis­abled applic­ants will be given pref­er­ence in the case of equi­val­ent qual­i­fic­a­tions. An exten­ded cer­ti­fic­ate of good con­duct must be sub­mit­ted. Any travel expenses incurred can­not be reim­bursed.
Data pro­tec­tion notice: The Char­ité points out that, within the frame­work and for the pur­poses of the applic­a­tion pro­cess at vari­ous loc­a­tions within the Char­ité (e.g. depart­ment, per­son­nel rep­res­ent­a­tion, per­son­nel depart­ment) per­sonal data is stored and pro­cessed. Fur­ther­more, the data may be trans­ferred within the group as well as to places out­side (e.g. author­it­ies) for the pro­tec­tion of legit­im­ate interests. By sub­mit­ting your applic­a­tion, you agree to our data pro­tec­tion and usage reg­u­la­tions for applic­a­tion pro­ced­ures, which you can find here: https://www.charite.de/service/datenschutz/bewerbungsverfahren/.