The Institute employs multi-disciplinary approaches to infection biology, comprising concepts and methodologies of molecular genetics, immunology, cell biology, epidemiology, clinical research and protein chemistry. The Institute promotes the applications of its research towards paving the way for the design of rational measures of control of infectious diseases.
Student researcher position for physics, biophysics and computational scientists
The Taylor lab is looking for an enthusiastic and motivated undergraduate student to join our research group at the Max Planck Institute for Infection Biology located at the Charite Campus Mitte. This position is for a paid student researcher position in the lab. We are interested in students with a physics or engineering background that are motivated to apply their skill set to answer biological questions.
We currently have projects that are examining the molecular dynamics of immune signaling pathways using synthetic T cell receptors (see reference1), as well as projects exploring the protein dynamics of innate immune signaling. Students will apply their computational skills to develop tools to analyze microscopy data. Students in the lab will receive training in single-molecule imaging, and cellular engineering approaches developed in the lab1.
The successful candidate will have strong computational and data analysis skills. The candidate should be competent in MATLAB and Python programming. A background in image analysis and signal processing will also be valuable for this position. Any experience with biophysics, biochemistry or cell biology is advantageous, but not necessary. The main requirement is enthusiasm to learn and apply themselves to solve biological questions.
What we offer:
The Taylor laboratory is interested in how immune cells decode chemical information. We aim to understand how immunological signaling molecules self-organize to detect and respond to the molecular signals of disease and infection. We have developed assays and approaches that allow us to visualize the biochemistry of immune signal-ling at the single molecule level within live cells1. Our scientific vision is to leverage a detailed understanding of the molecular mechanism to be able to re-engineer and con-trol these signaling systems.
1. Taylor, M. J., Husain, K., Gartner, Z. J., Mayor, S. & Vale, R. D. A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination. Cell 169, 108–119.e20 (2017).