Freie Universität Berlin - Fachbereich Biologie, Chemie, Pharmazie - Institut für Chemie und Biochemie
The EU project GlycoSpec aims to investigate the reaction mechanism in glycosylation, which is crucial for building oligosaccharides. For this purpose, a detailed structural analysis of the sugar intermediate, the glycosyl cation, is required. The approach involves using a cryogenic helium droplet instrument to capture the intermediate in the gas phase. Subsequently, a laser irradiates the target ion, revealing its vibrational pattern. This mass spectrometry-based technology provides a snapshot of the SN1 mechanism. A series of chemical reactions are then conducted to correlate the gas-phase structure with the synthesis in solution.
Research assistant (postdoc) (m/f/d)
full-time job
limited to 31.01.2026 (end of project)
salary grade (Entgeltgruppe) 13 TV-L FU
reference code: WiMi-AGPagel_230
Working field:
- Design and synthesis of sugar building blocks with diverse functional group modifications
- develop and execute chemical reactions to probe the glycosylation mechanism
- perform in-depth spectrometric analysis of oligosaccharides using Nuclear Magnetic Resonance (NMR), mass spectrometry, and infrared spectroscopy (IR)
Requirements:
- Completed scientific degree (M.Sc. or Diploma) and completed doctorate in organic or carbohydrate chemistry
(Professional) Experience:
- Experience in carbohydrate chemistry
- experience in glycan synthesis
Desirable:
- Experience in the synthesis of oligosaccharides and mechanism studies in glycosylation reactions.
- proficient in written and spoken English.
How to apply:
We look forward to receiving your application, which should include the following documents:
- a one-page letter of motivation why you want to work in EU project GlycoSpec, together with details of previous research experience and future goals
- your CV (including a list of publications if applicable)
- evidence of your academic achievements including copies of your Bachelor's, Master's and PhD degrees
- at least two letters of support
Applications should be sent by e-mail, together with all documents listed above, indicating the reference code no later than October 21st 2024 in PDF format (preferably as one document) to Dr. Kevin Pagel: miriam.mahn@fu-berlin.de or postal to
Freie Universität Berlin
Fachbereich Biologie, Chemie, Pharmazie
Institut für Chemie und Biochemie
Frau Prof. Dr. Kevin Pagel
Altensteinstr. 23A
14195 Berlin (Dahlem)
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Freie Universität Berlin is an equal opportunity employer.
Facts
ID: 188028
- Site:
-
- Berlin (Berlin, Germany)
- Type:
- Research assistant
- Duration:
- limited to 31.01.2026 (end of project)
- Part-/Full-time:
- full-time job
- Starting date (earliest):
- At the earliest possible
- Remuneration:
- salary grade (Entgeltgruppe) 13 TV-L FU
- Scope:
- Chemistry
- Research
- Natural Sciences
- Field of studies:
- Natural sciences and mathematics
- Biochemistry
- Chemistry
- Working language and expected level:
-
- German (Very good command of the language)
Actions
Apply
- Closing date:
- 21/10/24
- Reference number:
- WiMi-AGPagel_230
- Contact person:
- Herr Prof. Dr. Kevin Pagel
- By post:
- Freie Universität Berlin
Fachbereich Biologie, Chemie, Pharmazie
Institut für Chemie und Biochemie
Herrn Prof. Dr. Kevin Pagel
Altensteinstr. 23A
14195 Berlin (Dahlem) - By email:
- miriam.mahn@fu-berlin.de