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Offer 313 out of 641 from 11/05/22, 17:00

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Tech­ni­sche Uni­ver­sität Ber­lin - Fac­ulty II - Insti­tute of Chem­istry / Max-Vol­mer-Labo­ra­to­ry for Bio­phy­sical Che­mis­try

Research Assistant (PostDoc) - salary grade E13 TV-L Berliner Hochschulen

part-time employment may be possible

Postdoctoral position is available immediately in the Biomolecular Modelling Group (Institute of Chemistry) at the Technische Universität Berlin. Research will take place in Berlin, Germany within a close collaboration with the University of Kentucky (USA) under the joint supervision of Prof. M. A. Mroginski (TU Berlin) and Prof. A.-F. Miller (Kentucky).

Working field:

The object of the study is an electron transfer flavoprotein containing two non-covalently bound FADs. The goals of the study include elucidation of proton transfer coupled to electron transfer and attendant reorganization of hydrogen bond networks that could trigger conformational change in the protein, upon reduction of one or other of the two flavins. The candidate will apply molecular dynamics methods to investigate the possibility of domain-scale motion associated with reorganization of hydrogen bond networks, and ab initio methods to investigate possible coupling between these and electronic properties and redox states of the flavin.

Questions: afmill3r2@gmail.com or andrea.mroginski@tu-berlin.de.

Requirements:

Successfully completed university degree (Master, Diplom or equivalent) and PhD in physics, chemistry, biochemistry or in bioinformatics; experience with computational methods such as QMMM and MD. Strong background in programming and administration of HPC systems. Very good command of the English language (written and spoken); willingness to learn German is expected.
Desired qualifications: Experience with ab initio calculations of excited states and prediction of residue pKs are desirable.

How to apply:

Please send your application with the reference number and the usual documents (combined in a single pdf file, max 5 MB) by email to Prof. Dr. Maria Andrea Mroginski at andrea.mroginski@tu-berlin.de.

By submitting your application via email you consent to having your data electronically processed and saved. Please note that we do not provide a guarantee for the protection of your personal data when submitted as unprotected file. Please find our data protection notice acc. DSGVO (General Data Protection Regulation) at the TU staff department homepage: https://www.abt2-t.tu-berlin.de/menue/themen_a_z/datenschutzerklaerung/ or quick access 214041.

To ensure equal opportunities between women and men, applications by women with the required qualifications are explicitly desired. Qualified individuals with disabilities will be favored. The TU Berlin values the diversity of its members and is committed to the goals of equal opportunities.

Technische Universität Berlin - Die Präsidentin - , Fakultät II, Institut für Chemie, Max-Volmer-Laboratorium für Biophysikalische Chemie, Prof. Dr. Maria Andrea Mroginski, Sekr. C 7, Straße des 17. Juni 135, 10623 Berlin