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Tech­ni­sche Uni­ver­si­tät Dres­den - Cen­ter for Mole­cu­lar and Cel­lu­lar Bio­en­gi­nee­ring (CMCB), Cen­ter for Rege­ne­ra­tive The­ra­pies Dres­den (CRTD), Chair of Neural Deve­lop­ment and Rege­ne­ra­tion

The TU Dres­den is one of ele­ven Ger­man uni­ver­si­ties that were iden­ti­fied as an “excel­lence uni­ver­sity”. TUD has about 36.500 stu­dents and almost 5319 employees, 507 pro­fes­sors among them, and, thus, is the lar­gest uni­ver­sity in Sax­ony, today.

Having been com­mit­ted to sci­en­ces and the engi­nee­ring before the reuni­fi­ca­tion of Ger­many, TU Dres­den now is a multi-disci­pline uni­ver­sity, also offe­ring huma­nities and social sci­en­ces as well as medi­cine.

Rese­arch Asso­ciate / Post­doc

(Sub­ject to per­sonal qual­i­fic­a­tion employ­ees are remu­ner­ated accord­ing to salary group E 13 TV-L)

Work­ing field:

The pos­i­tion is offered in the newly estab­lished Chair of Neural Devel­op­ment and Regen­er­a­tion (Prof. Cath­er­ina Becker) and is start­ing as soon as pos­sible. The pos­i­tion is ini­tially lim­ited for 3 years. The period of employ­ment is gov­erned by the Fixed Term Research Con­tracts Act (Wis­senschaft­szeitver­trags­ge­setz - Wis­sZeitVG). The pos­i­tion aims at obtain­ing fur­ther aca­demic qual­i­fic­a­tion (e.g. habil­it­a­tion thesis).
The Research Cen­ter for Regen­er­at­ive Ther­apies Dresden con­sists of more than 80 research groups work­ing in the field of haemat­o­logy, dia­betes, neuro­de­gen­er­at­ive dis­eases and bone regen­er­a­tion. The CRTD explores the capa­city for regen­er­a­tion of the human body and aims to develop novel regen­er­at­ive ther­apies, e.g. with hem­at­o­lo­gical stem cells. In order to be able to develop such ther­apies, the research insti­tute explores mech­an­isms of stem cell physiology in vitro as well as in vivo using animal mod­els such as mouse, axo­lotl and zebrafish.
The newly estab­lished pro­fess­or­ship of Prof. Becker is look­ing for post-doc­toral research­ers at any level who want to get involved in the efforts to elu­cid­ate mech­an­ism of spinal cord repair (Cavone et al, Dev Cell, 2021, Tsa­rouchas et al., Nature Com­mun 2018; Wehner et al., Nature Com­mun 2017) and neuro­de­gen­er­at­ive dis­eases (Oprişoreanu et al., Cell Reports 2019) by mak­ing full use of the exper­i­mental advant­ages of the zebrafish model.

  • Elab­or­a­tion of new the­or­et­ical know­ledge with the aim of devel­op­ing new sci­entific meth­ods to identify factors (genes, lig­ands, recept­ors, and cells) that pro­mote regen­er­at­ive neuro­gen­esis (regen­er­at­ive neuro­gen­esis), or stim­u­late axonal growth;
  • gen­er­a­tion and char­ac­ter­iz­a­tion of CRISPR/Cas9 zebrafish mutants;
  • breed­ing and man­age­ment of mutants and trans­genic fish lines (gen­o­typ­ing, cross­ing and doc­u­ment­a­tion of lines);
  • animal exper­i­mental activ­it­ies (beha­vi­oral ana­lysis of zebrafish mutants);
  • immun­o­his­to­chem­ical, molecu­lar bio­lo­gical, bio­chem­ical and genetic invest­ig­a­tion meth­ods;
  • qRT-PCR of FACS-sor­ted neur­onal pro­gen­itor cells and immune cells;
  • per­form­ance of spinal cord lesions in zebrafish lar­vae;
  • ana­lyses of dif­fer­ent gene expres­sion pat­terns in immune cells and neur­onal cells by RNA­scope or by clas­sical in situ hybrid­iz­a­tion (ISH).

Require­ments:

  • the can­did­ate is highly motiv­ated with a uni­versity degree (bio­logy, bio­chem­istry, medi­cine, or inform­at­ics) and suc­cess­fully com­pleted PhD (bio­logy or related field).
  • Good know­ledge of both spoken and writ­ten Eng­lish is a require­ment.
  • Famili­ar­ity with the exper­i­mental model is an advant­age, but not a pre-requis­ite.

How to ap­ply:

Applic­a­tions from women are par­tic­u­larly wel­come. The same applies to people with dis­ab­il­it­ies.
Please sub­mit your com­pre­hens­ive applic­a­tion includ­ing the usual doc­u­ments by July 9, 2021 (stamped arrival date applies) prefer­ably via the TU Dresden Secure­Mail Portal https://securemail.tu-dresden.de by send­ing it as a single pdf doc­u­ment to

eike.lau@tu-dresden.de

or by mail to:

TU Dresden
CRTD
Pro­fes­sur für Neur­onale Entwicklung und Regen­er­a­tion
Frau Prof. Cath­er­ina Becker
Fetscher­straße 105
01307 Dresden.

Please sub­mit cop­ies only, as your applic­a­tion will not be returned to you. Expenses incurred in attend­ing inter­views can­not be reim­bursed.

Ref­er­ence to data pro­tec­tion: Your data pro­tec­tion rights, the pur­pose for which your data will be pro­cessed, as well as fur­ther inform­a­tion about data pro­tec­tion is avail­able to you on the web­site: https: //tu-dresden.de/kar­ri­ere/datens­chutzh­in­weis