An­ge­bot 161 von 314 vom 20.03.2020, 11:24


Cha­rité Uni­ver­si­täts­me­di­zin Ber­lin - CC13 - Innere Medi­zin mit Gas­tro­en­te­ro­lo­gie und Nephrolo­gie

The Cha­rité - Uni­ver­si­täts­me­di­zin Ber­lin is a joint medi­cal faculty, which ser­ves both Freie Uni­ver­si­tät Ber­lin and Hum­boldt Uni­ver­si­tät zu Ber­lin. As one of the lar­gest uni­ver­sity hos­pi­tals in Europe with an important history, it plays a lea­ding role in rese­arch, tea­ching and cli­ni­cal care. The Cha­rité uni­ver­sity hos­pi­tal has also made a name for its­elf as a modern busi­ness with cer­ti­fi­ca­ti­ons in the medi­cal, cli­ni­cal and manage­ment fields.
The DFG-fun­ded Rese­arch Trai­ning Group (GRK 2318) “TJ-Train” at the Insti­tute of Cli­ni­cal Phy­sio­logy (Cha­rité­Cen­ter 13, Cen­ter Inter­nal Medi­cine with Gas­tro­en­te­ro­logy and Nephrology) is loo­king for PhD stu­dents. 3 pro­ject areas offer rese­arch on dif­fe­rent aspects of tight junc­tions (TJ) in epi­the­lial bar­rier func­tion. Pro­ject area A com­pri­ses basic rese­arch on struc­ture and func­tion of TJ pro­te­ins, which pro­vi­des the requi­re­ment for under­stan­ding TJ deve­lop­ment and regu­la­tion and its role in patho­ge­ne­sis of disease. Pro­ject area B focu­ses on the role of TJ pro­te­ins in the deve­lo­ping tis­sue and the regu­la­tion of TJ pro­te­ins and TJ assem­bly on dif­fe­rent levels. Pro­ject area C
focu­ses on modu­la­tion of TJ in infec­tious and inflammatory intes­ti­nal disease asso­cia­ted with bar­rier dys­func­tion. Infor­ma­tion con­cer­ning the pro­jects here:

10 PhD Posi­ti­ons in life sci­ence

Work­ing field:

  • Plan­ning, orga­ni­za­tion and imple­men­ta­tion of sci­en­ti­fic stu­dies
  • The methods are depen­dent on the pro­jects and include cell cul­ture, mole­cu­lar and immuno­histo­che­mi­cal methods, con­fo­cal micro­scopy, high-reso­lu­tion micro­scopy, next-genera­tion sequen­cing, expe­ri­men­tal ani­mal methods, knock­out mouse models, elec­tro­phy­sio­lo­gi­cal tech­ni­ques
  • Inde­pen­dent eva­lua­tion and docu­men­ta­tion of the results
  • Wri­ting of sci­en­ti­fic publi­ca­ti­ons
  • Par­ti­ci­pa­tion in sci­en­ti­fic events and pre­sen­ta­tion of results at con­gres­ses
  • Par­ti­ci­pa­tion in the qua­li­fi­ca­tion pro­gram of the Rese­arch Trai­ning Group


  • Very good Uni­ver­sity degree (equi­va­lent diploma/mas­ter) in bio­logy, bio­che­mi­stry, bio­tech­no­logy, bio­in­for­ma­tics, bio­phy­sics or a rela­ted sub­ject
  • Strong sci­en­ti­fic moti­va­tion
  • Spe­cial inte­rest in cell bio­logy and in func­tio­nal and patho­phy­sio­lo­gi­cal-trans­la­tio­nal issues
  • Very good com­mu­ni­ca­tion and wri­ting skills in Eng­lish
  • Per­so­nal initia­tive, skills in team­work, orga­ni­za­tion and logistics

How to ap­ply:

Please send your applic­a­tion quot­ing the ref­er­ence num­ber to:
(only one pdf doc­u­ment, inform­a­tion con­cern­ing the require­ments of your applic­a­tion here:

DIE CHAR­ITÉ – UNI­VERSITÄTSMED­IZIN BER­LIN makes its human resources decisions based on
suit­ab­il­ity, com­pet­ence and pro­fes­sional per­form­ance. At the same time, it strives to increase the per­cent­age of women in man­age­ment pos­i­tions and takes this into con­sid­er­a­tion where can­did­ates are equally qual­i­fied within the lim­its of what is leg­ally pos­sible. Applic­a­tions from people with a migrant back­ground are also expli­citly wel­come. Severely dis­abled applic­ants are given pref­er­en­tial con­sid­er­a­tion in the case of can­did­ates with equal qual­i­fic­a­tions. An exten­ded cer­ti­fic­ate of con­duct must be sub­mit­ted. Any travel expenses incurred can­not be reim­bursed.
Data pro­tec­tion notice: Char­ité points out that per­sonal data is stored and pro­cessed as part of the applic­a­tion pro­cess in dif­fer­ent areas of Char­ité (e.g. fac­ulty, staff com­mit­tee, human resources depart­ment). Fur­ther­more, the data may be trans­ferred or pro­cessed within the group as well as in loc­a­tions out­side the group (e.g. author­it­ies) to pro­tect legit­im­ate interests. By apply­ing, you agree to our data pro­tec­tion reg­u­la­tions and terms of use, which you can find here.