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An­ge­bot 269 von 399 vom 02.04.2019, 11:42

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Lehr­stuhl für Bio­lo­gi­sche Bild­ge­bung an der Techi­schen Uni­ver­si­tät Mün­chen

Are you pas­sion­ate about sci­ence, full of ideas and innov­at­ive poten­tial that drive change and enjoy work­ing in an inter­na­tional, fast-paced envir­on­ment? Are you motiv­ated by the soci­etal impact of research and seek an oppor­tun­ity to play an instru­mental part in the devel­op­ment of emer­ging tech­no­lo­gies for bio­logy and health­care? Then the Chair of Bio­lo­gical Ima­ging (CBI) at the Tech­nical Uni­versity of Munich (TUM) and its integ­rated Insti­tute of Bio­lo­gical and Med­ical Ima­ging (IBMI) at the Helm­holtz Zen­trum Muenchen (HMGU), Ger­many, is the ideal envir­on­ment for you! We are now team­ing up with the II Med­ical Depart­ment of the Klinikum rechts der Isar of TUM to pro­pel clin­ical trans­la­tion to the next level.
CBI is the corner­stone of a rap­idly expand­ing bioen­gin­eer­ing eco­sys­tem in the Munich sci­ence area; includ­ing the Research Cen­ter Trans­laTUM and the Helm­holtz Pion­eer Cam­pus, which integ­rate bioen­gin­eer­ing with onco­logy and meta­bolic dis­orders, respect­ively. CBI sci­ent­ists develop next-gen­er­a­tion ima­ging and sens­ing meth­ods to meas­ure pre­vi­ously inac­cess­ible prop­er­ties of liv­ing sys­tems, hence, cata­lyz­ing break­throughs in bio­logy and medi­cine. Com­pris­ing 11 inter-dis­cip­lin­ary labor­at­or­ies and sci­ent­ists from more than 25 coun­tries, CBI offers state-of-the-art infra­struc­ture for innov­at­ive research and a per­fect envir­on­ment to accel­er­ate your career. Our research aims to shift the paradigm of bio­lo­gical dis­cov­ery and trans­la­tion to address major health chal­lenges of our time and develop the med­ical solu­tions of tomor­row.
The Klinikum rechts der Isar of TUM is loc­ated in the city centre of Munich and a lead­ing insti­tu­tion of higher edu­ca­tion and research. The II Med­ical Depart­ment at Klinikum rechts der Isar is ded­ic­ated to the dis­cov­ery of pathomech­an­isms of gut related dis­eases with a strong emphasis on inflam­ma­tion-induced can­cer form­a­tion.
Join our inter­dis­cip­lin­ary team and be part of our rich and dynamic research cul­ture of enquiry and innov­a­tion. CBI research­ers come from the top ranks of phys­ics, engin­eer­ing, chem­istry and bio­medi­cine and our pipeline fre­quently yields high-impact papers, suc­cess­ful tech­no­logy spin-offs and com­mer­cial­iz­a­tion. Our research is reg­u­larly fea­tured in major news chan­nels and received broad recog­ni­tion includ­ing sev­eral pres­ti­gi­ous awards and con­sid­er­able research fund­ing from national and inter­na­tional sources.

Postdoc­toral fel­low in molecu­lar mouse bio­logy and ima­ging (f/m/d)

We now seek a highly qual­i­fied and motiv­ated postdoc­toral fel­low (f/m/d) to drive the devel­op­ment of novel animal mod­els for gastrointest­inal tract can­cer and ima­ging mod­al­it­ies based on Raman and Scat­ter­ing in a joint research pro­ject together with the II Med­ical Depart­ment at Klinikum rechts der Isar.

Work­ing field:

Can­cer is a major cause of death world­wide and gastrointest­inal (GI) tract tumors are among the most com­mon and dead­li­est ones, account­ing for over 20% of newly dia­gnosed cases and 15% of fatal­it­ies. Des­pite recent pro­gress in dia­gnosis and ther­apies, the socio-eco­nomic impact of can­cer is enorm­ous. All parties in the health sec­tor agree that pre­ven­tion and/or early dia­gnosis is the most effect­ive means to deal with can­cer; yet until today, malig­nant tumors are most often only iden­ti­fied when symp­to­matic or large enough to be vis­ible in body scans or when his­to­lo­gical alter­a­tions are already present. Until now, we are urgently miss­ing an ima­ging method that detects tis­sue changes and facil­it­ates or pre­dicts tumor devel­op­ment at an early stage.
These alter­a­tions, col­lect­ively referred to as “field can­cer­iz­a­tion”, are an excit­ing field of study in can­cer bio­logy with pro­found rami­fic­a­tions in clin­ical prac­tice. This is a highly trans­la­tional pro­ject with focus on molecu­lar mouse bio­logy in GI car­ci­no­gen­esis and ima­ging tech­no­lo­gies.
The suc­cess­ful can­did­ate will develop animal mod­els for GI tract can­cer and will gain hands-on exper­i­ence with ima­ging mod­al­it­ies like Raman, Scat­ter­ing, and Fluor­es­cence. All sys­tems will be built upon cur­rent expert­ise and pre­lim­in­ary data and will be the world’s first to demon­strate detec­tion of “field-can­cer­iz­a­tion” based on molecu­lar bio­mark­ers. The pro­ject aims to inter­rog­ate the link between struc­tural and molecu­lar changes in epi­thelial tis­sues dur­ing the early stages of the tum­ori­gen­esis pro­cess.

Require­ments:

The suc­cess­ful applic­ant must have the fol­low­ing:
  • A Ph.D. in Bio­logy or related dis­cip­line.
  • Excel­lent track record of research achieve­ment and pub­lic­a­tions in top-ranked journ­als
  • Strong motiv­a­tion, sci­entific curi­os­ity and com­mit­ment to sci­entific excel­lence
  • Exper­i­ence in an area of bio­logy, micro­scopy, or sim­ilar area, prefer­able with back­ground or interest to develop exper­i­mental pro­to­cols and apply them to meas­ure­ments and data inter­pret­a­tion
  • In-depth know­ledge of mouse bio­logy and hand­ling, exper­i­ence with genet­ic­ally engin­eered mouse mod­els and ana­lysis of molecu­lar path­ways in car­ci­no­gen­esis
  • Team player skills and enthu­si­asm to work in a multi-dis­cip­lin­ary, col­lab­or­at­ive envir­on­ment
  • Excel­lent com­mand of the Eng­lish lan­guage

What we of­fer:

We offer you the unique chance to make a dif­fer­ence in future health­care. At CBI, we strongly believe in sci­entific excel­lence and innov­a­tion. This is your oppor­tun­ity to be part of and to advance your career in a world-lead­ing research insti­tute, where bioen­gin­eer­ing prin­ciples meet today’s chal­lenges in bio­logy and medi­cine to develop the solu­tions of tomor­row. CBI provides a highly inter­na­tional, multi-dis­cip­lin­ary envir­on­ment with excel­lent oppor­tun­it­ies for pro­fes­sional growth. You will be part of a dynamic, pro­fes­sional and highly motiv­ated team within a stim­u­lat­ing envir­on­ment. We sup­port career devel­op­ment, con­tin­ued edu­ca­tion and life-long learn­ing.
Situ­ated on the foot­hills of the Alps, Munich is con­sist­ently ranked as one of the most vibrant and enjoy­able cit­ies in the world, with an excep­tion­ally qual­ity of life. Greater Munich is also home to sev­eral world-class uni­versit­ies and research insti­tutes, cre­at­ing a truly inspir­ing intel­lec­tual atmo­sphere.

The suc­cess­ful applic­ant will ini­tially have a 2-year con­tract, with the pos­sib­il­ity of exten­sion. We offer a com­pet­it­ive salary and bene­fits depend­ing on work exper­i­ence and seni­or­ity in accord­ance with the pub­lic ser­vice wage agree­ment of the Free State of Bav­aria (TV L E-13). As an equal oppor­tun­ity and affirm­at­ive action employer, TUM expli­citly encour­ages applic­a­tions from women as well as from all oth­ers who would bring addi­tional diversity dimen­sions to the uni­versity’s research and teach­ing strategies. Pref­er­ence will be given to dis­abled can­did­ates with essen­tially the same qual­i­fic­a­tions.

How to ap­ply:

We are look­ing for­ward to receiv­ing your com­pre­hens­ive applic­a­tion includ­ing your let­ter of motiv­a­tion, CV and aca­demic tran­scripts of records, prefer­ably in Eng­lish and in a single PDF file via email to cbi.recruitment@tum.de. Please indic­ate “Postdoc­toral fel­low in molecu­lar mouse bio­logy and ima­ging (f/m/d)” in the sub­ject line.